Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors

H Motiwala, S Kandre, V Birar, KS Kadam…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5812 - 5817

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Citation Number: 11

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... a Department of Medicinal Chemistry, Piramal Life ... is essential for the accumulation of adipose tissue, inhibition of triglyceride synthesis may act as a strategy to either prevent or reverse obesity and its related medical consequences. ...

Exploration of pyridine containing heteroaryl analogs of bia...

[Motiwala, Hashim; Kandre, Shivaji; Birar, Vishal; Kadam, Kishorkumar S.; Rodge, Atish; Jadhav, Ravindra D.; Mahesh Kumar Reddy; Brahma, Manoja K.; Deshmukh, Nitin J.; Dixit, Amol; Doshi, Lalit; Gupte, Amol; Gangopadhyay, Ashok K.; Vishwakarma, Ram A.; Srinivasan, Shaila; Sharma, Mamta; Nemmani, Kumar V.S.; Sharma, Rajiv Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5812 - 5817]