We first examined the transesterification of a wide range of structurally varied β-keto esters with 1-octanol (Table [1] ). When a mixture of methyl acetoacetate (5.0 mmol), 1-octanol (6.5 mmol), commercial toluene without any purification (10 mL) and a catalytic amount of CsF (0.5 mmol) was stirred at refluxing temperature for 18 hours, octyl acetoacetate was obtained in 93% yield (entry 1). ... Upon completion of the transesterification, the catalyst was ...
[Doyle, Michael P.; Westrum, Larry J.; Wolthuis, Wendelmoed N. E.; See, Marjorie M.; Boone, William P.; Bagheri, Vahid; Pearson, Matthew M. Journal of the American Chemical Society, 1993 , vol. 115, # 3 p. 958 - 964]
