Synthesis of novel benzo-1, 2, 5-thiadiazines, their antimicrobial activity and isomerization into benzo-1, 2, 4-triazines

PP Deohate, JP Deohate, BN Berad

Index: Deohate, Pradip P.; Deohate, Jyoti P.; Berad Journal of the Indian Chemical Society, 2004 , vol. 81, # 9 p. 775 - 777

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Abstract

Résumé/Abstract Benzo [c]-δ-aryl/alkylimino-1, 2, 5-thiadiazines (4a-g) have been obtained by the basification of henzo [c]-6-aryl/alkylimino-1, 2, 5-thiadlazine dihydroiodides (3a-g). The latter were synthesized by the oxidative cyclisation of substituted 1-aryl/alkyl-3-(2'- aminophenyl) thiocarbamides (2a-g) by ethanolic iodine. Compounds (4a-g) on acylation with acetic anhydride and glacial acetic acid in 1: 2 ratio afforded 2, 5-diacetyl derivatives ( ...