Synthesis of boron-substituted pyrimidines and borazaroquinazolines

DS Matteson, MS Biernbaum, RA Bechtold…

Index: Matteson,D.S. et al. Journal of Organic Chemistry, 1978 , vol. 43, # 5 p. 950 - 954

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Citation Number: 39

Abstract

Two approaches to the synthesis of boron-substituted pyrimidines and borazaroquinazolines (1) have been ex-plored First,(dibutoxybory1) ethene and bromomalononitrile were converted to l, l-dicyano-3-bromo-3-(dibutoxy-bory1) propane (2), which was reduced with triphenyltin hydride to l, l-dicyano-3-(dibutoxyboryl) propane (3), which condensed with thiourea to yield 2-mercapto-4, 6-diamino-5-(2-dihydroxyborylethyl) ...