Several years ag0, Q we reported the synthesis and biological activity of a series of 2 (5H)- furanones 2 which were obtained by the rearrangement of 2-(substituted amino)-4, 5- dihydro-4-oxo-3-furancarboxylic acids 1, in the presence of NJV-bis (2-oxo-3-oxazolidinyl) phasphorodia-midic chloride (BOP-C1) and a substituted aromatic amine (Scheme I). During efforta to investigate the scope of this reaction, the preparation of 2-[(2-aminophenyl) ...
