Amino Diol HIV Protease Inhibitors. 1. Design, Synthesis, and Preliminary SAR

JC Barrish, E Gordon, M Alam, PF Lin…

Index: Journal of Medicinal Chemistry, , vol. 37, # 12 p. 1758 - 1768

Full Text: HTML

Citation Number: 65

Abstract

... Bethanne M. Warrack,* Richard J. Colonno) and Robert Zahlert Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey 08543-4000 Received February 16, 1994' ... 1 Journal of Medicinal Chemistry, 1994, Vol. 37, No. 12 1769 ...

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13734-34-4

Boc-L-phenylalanine

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(2R,3S)-3-(tert-Butoxycarbonylamino)-1-chloro-2-hydroxy-4-phenylbutane Structure

162536-40-5

(2R,3S)-3-(tert...

Boc-L-Phe-CHN2 Structure

60398-41-6

Boc-L-Phe-CHN2

~%

(2R,3S)-3-(tert-Butoxycarbonylamino)-1-chloro-2-hydroxy-4-phenylbutane Structure

162536-40-5

(2R,3S)-3-(tert...

Boc-Phe-O-COO-isoBu Structure

67729-36-6

Boc-Phe-O-COO-isoBu

~%

(2R,3S)-3-(tert-Butoxycarbonylamino)-1-chloro-2-hydroxy-4-phenylbutane Structure

162536-40-5

(2R,3S)-3-(tert...

Boc-L-phenylalanine Structure

13734-34-4

Boc-L-phenylalanine

~%

tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl)carbamate Structure

165727-45-7

tert-Butyl ((2S...

Boc-L-Phe-CHN2 Structure

60398-41-6

Boc-L-Phe-CHN2

~%

tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl)carbamate Structure

165727-45-7

tert-Butyl ((2S...

Boc-Phe-O-COO-isoBu Structure

67729-36-6

Boc-Phe-O-COO-isoBu

~%

tert-Butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl)carbamate Structure

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tert-Butyl ((2S...

ZL-Phe-CHN2 Structure

15196-02-8

ZL-Phe-CHN2

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128018-43-9

(2S,3S)-2-AMINO...


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