Advanced Synthesis & Catalysis

Thioethers as Directing Group for the Palladium??Catalyzed Direct Arylation of Arenes

J Yao, M Yu, Y Zhang

Index: Yao, Jinzhong; Yu, Ming; Zhang, Yuhong Advanced Synthesis and Catalysis, 2012 , vol. 354, # 17 p. 3205 - 3210

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Citation Number: 25

Abstract

Abstract Thioethers have proven to be efficient directing groups for the arylation of arenes under palladium catalysis. The thioether group can be readily removed or converted to other functional groups. Kinetic isotopic effect studies reveal that the C [BOND] H cleavage of arenes might be the turnover-limiting step.