A highly efficient and chemoselective synthetic protocol for tetrahydropyranylation/depyranylation of alcohols and phenols

…, E Mondal, BM Borah, S Ghosh

Index: Khan, Abu T.; Mondal, Ejabul; Borah, Ballav M.; Ghosh, Subrata European Journal of Organic Chemistry, 2003 , # 21 p. 4113 - 4117

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Citation Number: 35

Abstract

Abstract Various alcohols and phenols can be converted efficiently to the corresponding tetrahydropyranyl (THP) ethers in good yields using catalytic amounts of bromodimethylsulfonium bromide (0.005− 0.02 equivalent) at room temperature. On the other hand, various THP ethers can also be deprotected to the parent alcoholic or phenolic compounds in CH 2 Cl 2/MeOH (5: 2) by employing 0.05 equivalent of the same catalyst. ...