Monatshefte für Chemie/Chemical Monthly

Protoberberines from Reissert-Compounds. Part IX [1]. An Alternative Approach to Dibenzoquinolizine-and Isoquinonaphthyridin-13a-carboxylic Acids, a Novel …

E Reimann, F Grasberger

Index: Reimann, Eberhard; Grasberger, Fritz Monatshefte fur Chemie, 2005 , vol. 136, # 2 p. 193 - 209

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Citation Number: 8

Abstract

Summary. 3, 4-Dihydroisoquinoline-Reissert-compounds were alkylated to 1-benzyl-and 1- picolyl-derivatives, which in turn could selectively be hydrolized yielding various carboxylic acids, among others certain amino acids related to 3′, 4′-deoxynorlaudanosoline carboxylic acid (DNLCA). These on treating with ethanolic KOH underwent cyclization to dibenzoquinolizine-and isoquinonaphthyridine-13a-carboxylic acids. Alternatively this ...