Tetrahedron letters

An efficient, rapid and regioselective nuclear bromination of aromatics and heteroaromatics with NBS using sulfonic-acid-functionalized silica as a heterogeneous …

B Das, K Venkateswarlu, M Krishnaiah, H Holla

Index: Das, Biswanath; Venkateswarlu, Katta; Krishnaiah, Maddeboina; Holla, Harish Tetrahedron Letters, 2006 , vol. 47, # 49 p. 8693 - 8697

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Citation Number: 52

Abstract

A simple, efficient and rapid method has been developed for high-yielding regioselective nuclear monobromination of aromatic and heteroaromatic compounds using NBS in the presence of sulfonic-acid-functionalized silica at room temperature. The catalyst works under heterogeneous conditions and can be recycled.