Tetrahedron Letters

Synthesis of β-substituted α-iodo cycloalkanones by the CuI-mediated conjugate addition of Grignard reagents to α-iodo cycloalkenones

CK Sha, CT Tseng, WS Chang

Index: Sha, Chin-Kang; Tseng, Chen-Tso; Chang, Wen-Sheng Tetrahedron Letters, 2001 , vol. 42, # 4 p. 683 - 685

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Citation Number: 2

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... CuI-mediated conjugate addition of Grignard reagents to α-iodo cycloalkenones afforded β-substituted α-iodo cycloalkanones in good to excellent yields. ... Here we report results on conjugate addition of Grignard reagents to α-iodo cycloalkenones, which provides a new entry to β-substituted ...