Abstract Four series of p-(3, 5-diphenylpyrazole-1)-, p-[5-(p-chlorophenyl)-3-phenylpyrazole- 1]-, p-[5-(p-chlorophenyl)-4-hydroxy-3-phenyl-2-pyrazolin-1-yl]-, and p-[5-(p-chlorophenyl)-4- hydroxy-3-phenylpyrazole-1] benzenesulfonylurea derivatives were prepared for evaluation as hypoglycemic agents. Preliminary biological testing revealed that the new compounds possess potent hypoglycemic activity.