Synthesis and biological activity of some 5-heteromercapto-1, 2, 4-triazoles

EG Knysh, IA Mazur, NN Savenkova, VR Smets…

Index: Knysh, E. G.; Mazur, I. A.; Savenkova, N. N.; Smets, V. R.; Martynovskii, A. A. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 7 p. 476 - 479 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 7 p. 798 - 801

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Citation Number: 4

Abstract

The synthesis of the 5-heteromercapto-l, 2, 4-triazoles (Ia-d) was accomplished by reacting the substituted 5-mercapto-l, 2, 4-triazoles (Ia-d) with 4-bromoantipyrine (IIa), 2- chloromethylbenzimidazole (IIb), 2-chloroquinoline (IIc), 5-nitro-8-chloroquinoline (IId), and 2-ethoxy-6-nitro-9'chloroacridine (IIe)(see Table i).