e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron
The acid-catalyzed hydrolysis of 3-oxetanols: An hydroxymethyl group migration in the conversion of 2, 2, 3-trimethyl-3-oxetanol into 3-methyl-3-hydroxymethyl-2- …
The acetone photodimer 2, 2, 3-trimethyl-3-oxetanol was synthesized by photocyclization of isopropyloxyacetone and of 3-methyl-3-methoxy-2-butanone. The oxetanol was very sensitive to acids, and it rearranged to 3-hydroxymethyl-3-methyl-2-butanone by ring opening and migration of the hydroxymethyl group.
