Preparation of heteroaryloxetanes and heteroarylazetidines by use of a Minisci reaction

MAJ Duncton, MA Estiarte, RJ Johnson…

Index: Citterio, Attilio; Casucci, Domenico; Gentile, Anna; Serravalle, Marco; Ventura, Susanna Gazzetta Chimica Italiana, 1985 , vol. 115, # 6 p. 319 - 324

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Citation Number: 48

Abstract

... Volume: Page: ... A successful reaction with the marketed EGFR kinase inhibitor gefitinib(16) was also accomplished (entry 6). The results in Tables 1−3 are significant as they demonstrate that an oxetane, or azetidine, can be ... ring systems and substituted p.