Reaction of quinoxalin-2-ones with TosMIC reagent: synthesis of imidazo [1, 5-a] quinoxalin-4-ones

P Chen, JC Barrish, E Iwanowicz, J Lin, MS Bednarz…

Index: Chen, Ping; Barrish, Joel C.; Iwanowicz, Edwin; Lin, James; Bednarz, Mark S.; Chen, Bang-Chi Tetrahedron Letters, 2001 , vol. 42, # 26 p. 4293 - 4295

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Citation Number: 41

Abstract

Imidazo [1, 5-a] quinoxalin-4-ones were prepared in four steps starting from 1, 2- phenylenediamines using a new strategy for the construction of the ring system. A key step in this new method involves the reaction of quinoxalin-2-ones with TosMIC (tosylmethyl isocyanide).