e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Unsaturated macrocyclic compounds. LVIII. Reaction of trans-1, 4-dibromo-2-butene and trans-1, 4-dichloro-2-butene with ethynylmagnesium bromide. Synthesis of …
Y Gaoni, CC Leznoff, F Sondheimer
Index: Gaoni,Y. et al. Journal of the American Chemical Society, 1968 , vol. 90, # 18 p. 4940 - 4945
Abstract: Condensation between trans-l, 4-dibromo-2-butene (8) and an excess of ethynylmagnesium bromide (10) gave truns-4-octene-l, 7-diyne (14), as well as smaller amounts of truns, trans-4, 10-tetradecadiene-l, 7, 13-triyne (15) and uff-trans-4, 10, 16- eicosatriene-l, 7, 13, 19-tetrayne (16). Similarly, condensation between rruns-l, 4-dichloro-2- butene (9) and an excess of 10 led to 14 and 15. rruns-l-Bromo-2-hexen-5-yne (11) and ...
