Die Pharmazie

A convenient synthesis of new substituted pyrazolo [4, 3-c] quinolines with potential antiinflammatory activity.

R Mekheimer

Index: Mekheimer Pharmazie, 1994 ,  vol. 49,  # 7  p. 486 - 489

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Citation Number: 19

Abstract

2, 4-Dichloro-quinoline-3-carbonitrile 1 reacts with hydrazines to afford pyrazolo [4, 3-c] quinolines 5a, b. The reaction of 5a with sodium azide; hydrogen/Pd; triethylorthoformate; cyclohexylamine; piperidine; morpholine and acetic anhydride resulted in the corresponding heterocyclic derivatives 6-15.