Discovery of pyrano [3, 4-b] indoles as potent and selective HCV NS5B polymerase inhibitors

A Gopalsamy, K Lim, G Ciszewski, K Park…

Index: Journal of Medicinal Chemistry, , vol. 47, # 26 p. 6603 - 6608

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Citation Number: 82

Abstract

... Journal of Medicinal Chemistry. ... Current estimates of approximately 2.7−4 million people of the US population and 150 million worldwide as HCV carriers represent a significant medical problem with negative economic implications. ...