Kinetic resolution of racemic secondary alcohols via oxidation with Yarrowia lipolytica strains

…, M Fogagnolo, A Medici, P Pedrini, S Fontana

Index: Fantin, Giancarlo; Fogagnolo, Marco; Medici, Alessandro; Pedrini, Paola; Fontana, Silvia Tetrahedron Asymmetry, 2000 , vol. 11, # 11 p. 2367 - 2373

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Citation Number: 38

Abstract

Cyclic and alicyclic racemic secondary alcohols are kinetically resolved via oxidation with Yarrowia lipolytica strains. The comparison of the oxidation reactions with the reductions of the corresponding ketones supports the hypothesis of the presence of two alcohol dehydrogenases with opposite enantioselectivity.