A, 241, 147). In the first three cases yields were poor; in the last two no details or yields were given. Since the present work was carried out, a preparation in 70% yield from p- nitroacetophenone by reductive methylation has been described (Pearson and Bruson, J. Atner. Chein. Soc., 1951, 73, 864) but the unavailability of starting materials prevents its general application to homologues. There is one report (Skraup and Nieten, Ber., 1924, ...
[Chan, Louis K. M.; Poole, Darren L.; Shen, Di; Healy, Mark P.; Donohoe, Timothy J. Angewandte Chemie - International Edition, 2014 , vol. 53, # 3 p. 761 - 765 Angew. Chem., 2014 , vol. 126, # 3 p. 908]
![1-[4-(dimethylamino)phenyl]propan-1-one Structure](https://image.chemsrc.com/caspic/308/26672-58-2.png)