Convenient Preparation of O??Alkylhydroxamic Acids Using 2??Acylpyridazin??3 (2 H)??ones

JJ Kim, YD Park, HK Kim, SD Cho, JK Kim…

Index: Kim, Jeum-Jong; Park, Young-Dae; Kim, Ho-Kyun; Cho, Su-Dong; Kim, Ju-Kyeong; Lee, Sang-Gyeong; Yoon, Yong-Jin Synthetic Communications, 2005 , vol. 35, # 5 p. 731 - 738

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Citation Number: 7

Abstract

Abstract Treatment of O??alkylhydroxylamine hydrochlorides with 2??acyl??4, 5?? dichloropyridazin??3 (2 H)??ones in the presence of triethylamine or Amberlite® IRA??67 in acetonitrile gave corresponding O??alkylhydroxamic acid derivatives in excellent yields. This is an efficient, convenient, and eco??friendly method.