Canadian Journal of Chemistry

Modular incorporation of 1-benzyltryptophan into dipeptide hosts that bind acetylcholine in pure water

CS Beshara, F Hof

Index: Beshara, Cory S.; Hof, Fraser Canadian Journal of Chemistry, 2010 , vol. 88, # 10 p. 1009 - 1016

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Citation Number: 4

Abstract

Proteins that recognize and bind quaternary ammonium ions depend on “aromatic-cage” structural motifs that use multiple aromatic residues to engage the side chain's ammonium cation. We introduce herein the use of 1-benzyltryptophan (Trp (Bn)) residues as synthetic,