Stable Axial Chirality in Metal Complexes Bearing 4, 4'-Substituted BIPHEPs: Application to Catalytic Asymmetric Carbon-Carbon Bond-Forming Reactions

K Aikawa, Y Miyazaki, K Mikami

Index: Aikawa, Kohsuke; Miyazaki, Yoshitaka; Mikami, Koichi Bulletin of the Chemical Society of Japan, 2012 , vol. 85, # 2 p. 201 - 208

Full Text: HTML

Citation Number: 11

Abstract

Not only electronic but also steric effects of 4, 4′-substituents in BIPHEP derivatives and metal (Pd, Pt, and Au) complexes are shown to influence the stability of the biphenyl single bond rotation. While electron-donating or sterically demanding substituents on the 4, 4′- positions destabilize the axial chirality of BIPHEP derivatives, electron-withdrawing or sterically less demanding ones on the 4, 4′-positions stabilize the axis chirality. ...