In vitro activities of position 2 substitution-bearing 6-nitro-and 6-amino-benzothiazoles and their corresponding anthranilic acid derivatives against Leishmania …

…, C Detang, M Costa, P Timon-David…

Index: Delmas, Florence; Di Giorgio, Carole; Robin, Maxime; Azas, Nadine; Gasquet, Monique; Detang, Claire; Costa, Muriel; Timon-David, Pierre; Galy, Jean-Pierre Antimicrobial agents and chemotherapy, 2002 , vol. 46, # 8 p. 2588 - 2594

Full Text: HTML

Citation Number: 61

Abstract

ABSTRACT 6-Nitro-and 6-amino-benzothiazoles bearing different chains in position 2 and their corresponding anthranilic acid derivatives were investigated for their in vitro antiparasitic properties against parasites of the species Leishmania infantum and Trichomonas vaginalis compared to their toxicity towards human monocytes. Biological investigations established that the antiprotozoal properties depended greatly on the ...