Tetrahedron

Reduction of activated conjugated alkenes by the InCl 3–NaBH 4 reagent system

BC Ranu, S Samanta

Index: Ranu, Brindaban C.; Samanta, Sampak Tetrahedron, 2003 , vol. 59, # 40 p. 7901 - 7906

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Citation Number: 72

Abstract

A combination of a catalytic amount of indium (III) chloride and sodium borohydride in acetonitrile reduces selectively the carbon–carbon double bonds in conjugated alkenes such as α, α-dicyano olefins, α, β-unsaturated nitriles, cyanoesters, cyanophosphonate and dicarboxylic esters. However, reduction of chalcones is little different. They are reduced to a mixture of saturated ketones and alcohols if the reaction mixture is quenched with H2O, ...