Bioorganic & medicinal chemistry letters

Role of the hydrophobic moiety of tumor promoters. Synthesis and activity of 2-alkylated benzolactams

Y Endo, A Yokoyama

Index: Endo, Yasuyuki; Yokoyama, Akihiro Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 63 - 66

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Citation Number: 18

Abstract

The size and position of a hydrophobic moiety on a benzolactam skeleton, which reproduces the active conformation and biological activity of teleocidins, play an important role in the appearance of the activity. Compounds with alkyl groups of various sizes and ...