Dehalogenation of 1??methyl??5??halo??4??substituted??pyridazin??6??ones

DH Kweon, YJ Kang, HA Chung…

Index: Kweon, Deok-Heon; Kang, Young-Jin; Chung, Hyun-A.; Yoon, Yong-Jin Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 4 p. 819 - 826

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Citation Number: 19

Abstract

Abstract In order to confirm the regiochemistry for the functionalization of 1-(1, 1-dibromo-2- oxopropyl)-4, 5-dihalopyridazin-6-ones, the dehalogenation of 1-methyl-5-halo-4-substituted- pyridazin-6-ones using Pd/C and hydrogen was carried out. The results of the title reaction are reported.