Derivatives of benzo (c) fluorene: II. Synthesis and biological effect of basic ethers of 7-oxo-7H-benzo (c) fluorene

J Křepelka, I Vančurová, J Holubek…

Index: Krepelka; Vancurova; Holubek; et al. Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 7 p. 1856 - 1866

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Citation Number: 7

Abstract

Abstract Alkylation of phenols IIa-IIc with ω-(N, N-dialkylamino) alkyl chlorides IIIa-IIId in an aqueous and/or a two-phase (toluene and aqueous potassium hydroxide) medium, and reactions of phenols IId-IIf with isopropylamine, gave rise to ethers IV-XIX. Compounds IV and V were used to prepare derivatives XX-XXVI. Reduction of the 7-oxo group in the compound V by the action of sodium borohydride produced the 7-hydroxy derivatives ...