Abstract This study has tested the application of three different copolymeric poly(acry1amide-co- monoethyl itaconate; A/MEI) hydrogels, 90A/ 1 OMEI, 75A/25MEI and 60A/40MEI, on the release of cytarabine (ara-C). The drug was incorporated in gels by placing it in the polymerization feed mixture and discs loaded with 5-50 mg ara-C were obtained. The amount of swelling at equilibrium in saline solution (NaC1, 0.9% w/w) was between 78 ...
