Elucidation of the regio-and chemoselectivity of enzymatic allylic oxidations with Pleurotus sapidus–conversion of selected spirocyclic terpenoids and …

V Weidmann, M Schaffrath, H Zorn…

Index: Weidmann, Verena; Schaffrath, Mathias; Zorn, Holger; Rehbein, Julia; Maison, Wolfgang Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 2233 - 2241

Full Text: HTML

Citation Number: 10

Abstract

Abstract Allylic oxidations of olefins to enones allow the efficient synthesis of value-added products from simple olefinic precursors like terpenes or terpenoids. Biocatalytic variants have a large potential for industrial applications, particularly in the pharmaceutical and food industry. Herein we report efficient biocatalytic allylic oxidations of spirocyclic terpenoids by a lyophilisate of the edible fungus Pleurotus sapidus. This ''mushroom catalysis''is ...