Abstract A series of substituted N-(quinolin-4-yl) ethanediamine phenyl urea derivatives of biological interest were prepared by sequential quinoline synthesis, chlorination, and substitution reaction followed by reaction of resulting amine with different aryl isocyanates. All synthesized compounds (1–13) were screened for their pro-inflammatory cytokines (TNF- α and IL-6) and antimicrobial activity (antibacterial and antifungal). Biological activity ...
