Tetrahedron: Asymmetry

Enantioselective allylic alkylation using polymer-supported palladium catalysts

K Hallman, E Macedo, K Nordström, C Moberg

Index: Hallman, Kristina; Macedo, Emmanuel; Nordstroem, Kerstin; Moberg, Christina Tetrahedron Asymmetry, 1999 , vol. 10, # 20 p. 4037 - 4046

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Citation Number: 57

Abstract

Chiral 2′-(4 ″, 5 ″-dihydro-2 ″-oxazolyl)-6′-(1-hydroxyalkyl) pyridines were grafted via ester-linkages directly to cross-linked polystyrene and to polyethyleneglycol-containing resins TentaGel and ArgoGel functionalized with carboxylic acid groups or via spacers containing a carboxylic acid group. The polymeric ligands were used in the palladium- catalyzed substitution of rac-1, 3-diphenyl-2-propenyl acetate with dimethyl malonate. The ...