Journal of medicinal chemistry

… , biological evaluation, calcium channel antagonist activity, and anticonvulsant activity of felodipine coupled to a dihydropyridine-pyridinium salt redox chemical …

S Yiu, EE Knaus

Index: Yiu, Sai-Hay; Knaus, Edward E. Journal of Medicinal Chemistry, 1996 , vol. 39, # 23 p. 4576 - 4582

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Citation Number: 16

Abstract

3-(2-Hydroxyethyl) 5-methyl 1, 4-dihydro-2, 6-dimethyl-4-(2, 3-dichlorophenyl)-3, 5- pyridinedicarboxylate (7) was prepared using a modified Hantzsch reaction, which was then elaborated to 3-[2-[[(1-methyl-1, 4-dihydropyrid-3-yl) carbonyl] oxy] ethyl] 5-methyl 1, 4-