Synthesis

Regioselective syntheses of 7-halogenated 7-deazapurine nucleosides related to 2-amino-7-deaza-2′-deoxyadenosine and 7-deaza-2′-deoxyisoguanosine

F Seela, X Peng

Index: Synthesis, , # 8 p. 1203 - 1210

Full Text: HTML

Citation Number: 23

Abstract

... Two routes were employed for the synthesis of 7-halogenated 7-deazapurine nucleosides: (i) conversion of a preformed ... Compounds 5 and 11 were synthesized as described earlier. ... a little towards the N-population (around 70% S). In the case of the 7,8-dibromo-substituted ...