Synthesis and analgesic, anti-inflammatory activities of 3-(3-methoxyphenyl)-2-substituted amino-quinazolin-4 (3H)-ones

V Alagarsamy, M Gopinath, P Parthiban…

Index: Alagarsamy; Gopinath; Parthiban; Subba Rao; Murali; Raja Solomon Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 946 - 954

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Abstract

Abstract A variety of novel 3-(3-methoxyphenyl)-2-substituted amino-quinazolin-4 (3 H)-ones were synthesized by reacting the amino group of 2-hydrazino-3-(3-methoxyphenyl)- quinazolin-4 (3 H)-one with a variety of aldehydes and ketones. The starting material 2- hydrazino-3-(3-methoxyphenyl)-quinazolin-4 (3 H)-one was synthesized from 3-methoxy aniline. The title compounds were investigated for analgesic, anti-inflammatory, and ...