Chemoselectivity and Conformational Analysis of the Reaction of 2??Acetylcycloalkanones with Benzohydrazide: Synthesis and Reduction of 1??Aroylcycloalkapyrazole …

CA Tsoleridis, J Stephanidou??Stephanatou…

Index: Tsoleridis, Constantinos A.; Stephanidou-Stephanatou, Julia; Zika, Chara; Pozarentzi, Minothora; Alevizopoulos, Stephanos Helvetica Chimica Acta, 2003 , vol. 86, # 2 p. 330 - 342

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Citation Number: 9

Abstract

Abstract From the reaction of 2-acetylcyclopentanone and 2-acetyl-2-methylcyclopentanone with benzohydrazide, the 1-benzoyl-6a-hydroxycyclopentapyrazole derivatives 2a and 2b were obtained as the only reaction products, whereas from the reaction of 2- acetylcyclohexanone an epimeric cis/trans mixture of the 2-benzoyl-3-hydroxy-2H-indazole derivative 3c was formed. The dehydration of the isolated compounds 2a and 3c, as well ...