Annales UMCS Medicina 1996-01-01

[Reactions of 1-(X-benzoyl)-4R-thiosemicarbazide with chloroacetone and omega-bromoacetophenone. IV. 4-phenyl and 4-(p-tolyl)-thiosemicarbazide of o-chlorobenzoic acid].

E Bielak, S Biliński

Index: Ann. Univ. Mariae Curie. Sklodowska. Med. 51 , 167-76, (1996)

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Abstract

The reactions of 4-phenyl and 4-(p-tolyl)-thiosemicarbazide of o-chlorobenzoic acid (Ig, h) with chloroacetone and omega-bromoacetophenone were investigated in: methanolic medium (method D); methanolic medium in the presence of anhydrous CH3COONa (method E); methanolic medium in the presence of N(C2H5)3 (method F). In the methods E and F mercaptotriazoles Vg, h were obtained. The properties of compounds II ł-o and III ł-o were determined under the conditions of basic and acidic hydrolysis. The results of UV, IR and NMR spectroscopic measurements were reported.