Synthesis of functional aromatic multisulfonyl chlorides and their masked precursors

…, Y Sanai, J Smith, MN Holerca, B Barboiu…

Index: Percec; Bera; De Binod; Sanai; Smith; Holerca; Barboiu; Grubbs; Frechet Journal of Organic Chemistry, 2001 , vol. 66, # 6 p. 2104 - 2117

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Citation Number: 81

Abstract

The synthesis of functional aromatic bis (sulfonyl chlorides) containing an acetophenone and two sulfonyl chloride groups, ie, 3, 5-bis [4-(chlorosulfonyl) phenyl]-1-acetophenone (16), 3, 5-bis (chlorosulfonyl)-1-acetophenone (17), and 3, 5-bis (4-(chlorosulfonyl) phenyloxy)-1-acetophenone (18) via a sequence of reactions, involving in the last step the quantitative oxidative chlorination of S-(aryl)-N, N'-diethylthiocarbamate, alkyl-or benzyl ...