Nucleosides & nucleotides 1999-02-01

Synthesis and antiviral activity of novel aza-acyclonucleosides.

S C Bergmeier, S L Fundy, J C Drach

Index: Nucleosides Nucleotides 18 , 227, (1999)

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Abstract

We have prepared a series of novel aza-acyclonucleosides as potential antiviral agents. These compounds were prepared from diethanolamine and the desired purine or pyrimidine base via a Mitsunobu coupling. No antiviral activity was observed against either HSV-1 or HCMV.