New England Journal of Medicine 2015-01-08

Case records of the Massachusetts General Hospital. Case 1-2015. A 66-year-old woman with metastatic breast cancer after endocrine therapy.

Beverly Moy, Michelle C Specht, Michael Lanuti, Elizabeth A Rafferty, Melinda F Lerwill

Index: N. Engl. J. Med. 372(2) , 162-70, (2015)

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Abstract

In a 66-year-old woman, enlarged lymph nodes were seen on routine breast imaging. She had received a diagnosis of ductal carcinoma 6 years earlier and had been treated with radiation and chemotherapy, followed by anastrozole. A diagnostic procedure was performed. Presentation of Case Dr. Michelle C. Specht: A 66-year-old woman with a history of breast cancer was seen in the outpatient cancer center of this hospital 7 months after completion of adjuvant endocrine therapy because of changes seen on routine breast imaging. The patient had been well until 6 years before the current evaluation, when she noted a mass in the superolateral quadrant of the left breast. Dr. Elizabeth A. Rafferty: Mammography that was performed at the time of the initial presentation, 6 years previously, revealed extremely dense breast tissue but was otherwise normal (Figure 1A and 1B). Targeted ultrasound evaluation of . . .