Nonstabilized Azomethine Ylides Generated by Decarboxylative Condensation of α-Amino Acids. Structural Variation, Reactivity, and Stereoselectivity

S Kanemasa, K Sakamoto, O Tsuge

Index: Kanemasa, Shuji; Sakamoto,Kazushige; Tsuge, Otohiko Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 6 p. 1960 - 1968

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Citation Number: 34

Abstract

A variety of aldehydes, containing enolizable aldehydes other than acetaldehyde can be used in the generation method of nonstabilized azomethine ylides by decarboxylative condensation of α-amino acids. Reactivity of the nonstabilized ylides was examined in intermolecular and intramolecular cycloadditions with olefins; stereoselectivity of the intramolecular cycloaddition using nonstabilized ylides was compared with that of ester- ...