DDQ??Induced Dehydrogenation of Heterocycles for C C Double Bond Formation: Synthesis of 2??Thiazoles and 2??Oxazoles

…, C Li, B Yin, C Li, P Liu, J Li, Z Shi

Index: Li, Xiangnan; Li, Cheng; Yin, Bing; Li, Cong; Liu, Ping; Li, Jianli; Shi, Zhen Chemistry - An Asian Journal, 2013 , vol. 8, # 7 p. 1408 - 1411

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Abstract

Thiazoles and oxazoles represent a predominant structural motif in many natural compounds, organic dyes, and pharmaceuticals.[1–3] In recent years, thiazoles and oxazoles that are monosubstituted at the C2position have been widely used in organic synthesis as building blocks owing to their versatile reactivity.[4] However, a potential limitation for the application of 2-substituted thiazoles and oxazoles could be the lack of ...