Journal of Labelled Compounds and Radiopharmaceuticals 2015-04-01

Synthesis of deuterium-labelled isotopomer of deferasirox.

Freddy H Havaldar, Bhushan Vasant Dabholkar, Ganesh Baban Mule, Suhas Kulkarni

Index: J. Labelled Comp. Radiopharm. 58 , 163-5, (2015)

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Abstract

A d4 -labeled isotopomer of deferasirox was synthesized as internal standard for use in a LC/mass spectroscopy (MS)/MS method developed for the simultaneous quantitative determination of deferasirox in human serum. d4 -deferasirox was synthesized from d8 -toluene. Copyright © 2015 John Wiley & Sons, Ltd.