Ni??Catalyzed Cascade Cyclization–Kumada Alkyl–Alkyl Cross??Coupling

M Guisán??Ceinos, R Soler??Yanes…

Index: Guisan-Ceinos, Manuel; Soler-Yanes, Rita; Collado-Sanz, Daniel; Phapale, Vilas B.; Bunuel, Elena; Cardenas, Diego J. Chemistry - A European Journal, 2013 , vol. 19, # 26 p. 8405 - 8410

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Citation Number: 13

Abstract

Formation of CACHTUNGTRENNUNG (sp3) ÀCACHTUNGTRENNUNG (sp3) bonds by cross-coupling reactions has experienced an important development in recent years.[1] The intrinsic limitations associated with these kind of couplings, mainly the more difficult oxidative addition of alkyl electrophiles and the fast β-elimination of hydrogen in the alkyl– metal intermediates,[2] have been overcome in a variety of ways. Thus, in the Negishi and ...