Synthesis of benzamides, and their antispasmodic and antihypoxic properties

AA Bakibaev, VK Gorshkova, OV Arbit…

Index: Bakibaev, A. A.; Gorshkova, V. K.; Arbit, O. V.; Filimonov, V. D.; Saratikov, A. S. Pharmaceutical Chemistry Journal, 1994 , vol. 28, # 5 p. 335 - 338 Khimiko-Farmatsevticheskii Zhurnal, 1994 , vol. 28, # 5 p. 35 - 37

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Citation Number: 5

Abstract

Benzamides are known as physiologically active substances, and individual members of this series of compounds have found application as anticonvulsants, eg, metaclopramid (4- amino-5-chloro-N'-(2-diethylaminoethyl)-2-methoxybenzamide hydrochloride)[2], procainamide [4-amino-N-(2-diethylaminoethyl) benzamide][3] and its structural analogues [4, 5], which display pronounced antispasmodic activity. N-Aryltrimethoxybenzamides [6, 7 ...