Toxicology 2013-07-05

Prior oral exposure to environmental immunosuppressive chemicals methoxychlor, parathion, or piperonyl butoxide aggravates allergic airway inflammation in NC/Nga mice

R. Nishino, T. Fukuyama, Y. Tajima, L. Miyashita, Y. Watanabe, H. Ueda, T. Kosaka

Index: Toxicology 309 , 1-8, (2013)

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Abstract

• Allergic airway inflammation is aggravated by environmental chemicals methoxychlor, parathion, or piperonylbutoxide. • We investigated the association between immunosuppressive chemicals and development of allergic airway inflammation. • Using an animal model of ovalbumin-induced allergic airway inflammation in NC/Nga mice.