Conversion of a (sp 3) C–F bond of alkyl fluorides to (sp 3) C–X (X= Cl, C, H, O, S, Se, Te, N) bonds using organoaluminium reagents

…, SA Begum, Y Shinohara, M Tomita, Y Naitoh…

Index: Terao, Jun; Begum, Shameem Ara; Shinohara, Yoshiaki; Tomita, Masahiro; Naitoh, Yoshitaka; Kambe, Nobuaki Chemical Communications, 2007 , # 8 p. 855 - 857

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Citation Number: 35

Abstract

Organic fluorides, especially those having an (sp 3 )C–F bond, have been recognized as the most inert class of organic compounds due to the strong C–F bonds. Hence, to develop reactions which replace fluorine atoms with other atoms or groups is a challenging subject in organic chemistry. 1,2 It is known that (sp 3 )C–F bonds would be cleaved when treated with a strong hard acid in polar solvent and/or at elevated temperatures. Organoaluminium reagents or ...