Chemical Communications 2007-07-19

Palladium-catalysed regioselective addition reaction of ethyl phenylphosphinate with terminal acetylenes: ligand- and solvent-dependent regioselectivity.

Satish Kumar Nune, Masato Tanaka

Index: Chem. Commun. (Camb.) (27) , 2858-60, (2007)

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Abstract

Palladium-1,2-bis(diphenylphosphino)ethane complex catalyses regioselective Markovnikov addition of ethyl phenylphosphinate to terminal alkynes in toluene, while the use of tri-tert-butylphosphine as the ligand or ethanol as the solvent leads to regioselectivity reversal.