Chemical Communications 2005-09-21

Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates.

Hari M R Gardimalla, Deendayal Mandal, Philip D Stevens, Max Yen, Yong Gao

Index: Chem. Commun. (Camb.) (35) , 4432-4, (2005)

Full Text: HTML

Abstract

Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.